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How can models help explain minds and brains?

Computational approaches and AI

Topic guide · Computational approaches and AI / Cells, circuits and brains / Methods, evidence and reproducibility

How can a model help explain neural activity?

Connect modelling goals, simplified neuronal mechanisms, spike data and fitting exercises, with an optional route into network models.

Topic guide · Cells, circuits and brains / Learning, memory and education / Computational approaches and AI

How do synapses change a circuit’s response?

Separate transmission, short-term changes and longer-term learning rules before moving to networks.

Topic guide · Consciousness and philosophy / Methods, evidence and reproducibility / Computational approaches and AI

How can competing theories of consciousness be tested?

Distinguish a named theory, a particular prediction, a measurement and the interpretation of a result.

Lectures and explanations

Selections below prioritise source-checked annotations. Inclusion does not assess scientific correctness.

  1. MIT OpenCourseWare · Source-checked annotation

    2. RC Circuit and Nernst Potential

    MIT OpenCourseWare Michale Fee advanced 1 hr 20 min

    Models neuronal responses using membrane resistance, capacitance and an electrical-circuit analogy, introducing the source of neuronal potentials.

  2. MIT OpenCourseWare · Source-checked annotation

    11. Spectral Analysis Part 1

    MIT OpenCourseWare Michale Fee advanced 1 hr 18 min

    Introduces complex Fourier series, continuous and discrete transforms, and power spectra in a neural-computation course.

  3. MIT OpenCourseWare · Source-checked annotation

    14. Rate Models and Perceptrons

    MIT OpenCourseWare Michale Fee advanced 1 hr 15 min

    Introduces tractable network models through rate descriptions, receptive fields, vector algebra and perceptrons.

  4. Neuromatch Academy — Computational Neuroscience · Source-checked annotation

    Video 2: Response of ensemble of neurons to time-varying input

    Neuromatch Academy — Computational Neuroscience Speaker not established intermediate Duration unknown

    A bonus lecture on how an ensemble of neurons responds to input that varies over time, following a tutorial about shared inputs and correlations.

  5. MIT OpenCourseWare · Source-checked annotation

    4. Hodgkin-Huxley Model Part 1

    MIT OpenCourseWare Michale Fee advanced 1 hr 15 min

    Introduces the Hodgkin–Huxley circuit model through voltage-clamp measurements and the time and voltage dependence of potassium current.

  6. MIT OpenCourseWare · Source-checked annotation

    6. Dendrites

    MIT OpenCourseWare Michale Fee advanced 1 hr 6 min

    Extends circuit modelling to dendrites, spatial dimensions and a two-compartment representation.

  7. MIT OpenCourseWare · Source-checked annotation

    18. Recurrent Networks

    MIT OpenCourseWare Michale Fee advanced 1 hr 19 min

    Introduces mathematical descriptions of recurrent networks in relation to memory storage and decision-making.

  8. MIT OpenCourseWare · Source-checked annotation

    9. Receptive Fields

    MIT OpenCourseWare Michale Fee advanced 1 hr 18 min

    Introduces mathematical descriptions of responses to stimuli, including receptive fields, separability and spike-triggered averaging.

  9. Neuromatch Academy — Computational Neuroscience · Source-checked annotation

    Video 1: Phase analysis of the Wilson-Cowan E-I model

    Neuromatch Academy — Computational Neuroscience Speaker not established advanced Duration unknown

    Introduces the Wilson–Cowan model of interacting excitatory and inhibitory populations and its two-dimensional phase plane.

  10. MIT OpenCourseWare · Source-checked annotation

    20. Hopfield Networks

    MIT OpenCourseWare Michale Fee advanced 1 hr 13 min

    Examines attractor and winner-take-all networks, long-term memory models and Hopfield-network capacity.

  11. Neuromatch Academy — Computational Neuroscience · Source-checked annotation

    Video 1: Static and dynamic synapses

    Neuromatch Academy — Computational Neuroscience Speaker not established intermediate Duration unknown

    Introduces static and dynamic synapses, with a notebook that contrasts fixed connection strengths with short-term facilitation and depression.

  12. MIT OpenCourseWare · Source-checked annotation

    12. Spectral Analysis Part 2

    MIT OpenCourseWare Michale Fee advanced 1 hr 12 min

    Moves from Fourier transforms to estimating spectra, filtering signals in the frequency domain and removing line noise.

  13. Neuromatch Academy — Computational Neuroscience · Source-checked annotation

    Video 1: Linear Regression & Mean Squared Error

    Neuromatch Academy — Computational Neuroscience Speaker not established intermediate Duration unknown

    Introduces linear regression and mean squared error within a Neuromatch tutorial that asks learners to calculate error and fit a model parameter.

  14. Brain Inspired · Source-checked annotation

    BI 249 Michael Cole: Brain Flows are the Units of Cognition

    Brain Inspired Michael Cole; Paul Middlebrooks mixed Duration unknown

    Michael Cole discusses a view of cognition centred on flows of activity between brain regions and their network organisation.

  15. Neuromatch Academy — Computational Neuroscience · Source-checked annotation

    Video 1: Fixed points and their stability

    Neuromatch Academy — Computational Neuroscience Speaker not established advanced Duration unknown

    Extends the two-population model to fixed points, local stability, oscillatory behaviour and inhibition-stabilised regimes.

  16. MIT OpenCourseWare · Source-checked annotation

    5. Hodgkin-Huxley Model Part 2

    MIT OpenCourseWare Michale Fee advanced 1 hr 19 min

    Continues the Hodgkin–Huxley model, voltage-clamp analysis and the role of conductance in describing current.

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